Liquid biopsy, diagnostic imaging, and future synergies Journal Article
| Authors: | Petranovic, M.; Raoof, S.; Digumarthy, S. R.; Sharma, A.; Shepard, J. A. O.; Gainor, J. F.; Pandharipande, P. V. |
| Article Title: | Liquid biopsy, diagnostic imaging, and future synergies |
| Abstract: | Imaging plays an integral role in the initial diagnosis and longitudinal care of patients with cancer. Liquid biopsies, which most commonly involve genetic analysis of circulating free DNA, have emerged as important complementary tools in cancer care with the potential to interface with imaging at each step of the cancer care continuum. Here, the authors use non-small-cell lung cancer as a paradigm to elucidate factors driving the need for liquid biopsy in the spectrum of lung cancer care, demonstrate ways in which liquid biopsy has already changed standard clinical practice, and discuss anticipated synergies of liquid biopsy and imaging in screening and early detection and in monitoring of disease. © 2021 American College of Radiology |
| Keywords: | cancer staging; cancer diagnosis; clinical practice; lung cancer; diagnostic imaging; screening; genomics; imaging; plasma; non small cell lung cancer; lung parenchyma; high throughput sequencing; human; article; liquid biopsy; chloroplast dna; multicancer early detection |
| Journal Title: | Journal of the American College of Radiology |
| Volume: | 19 |
| Issue: | 2 |
| ISSN: | 1546-1440 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2022-02-01 |
| Start Page: | 336 |
| End Page: | 343 |
| Language: | English |
| DOI: | 10.1016/j.jacr.2021.11.001 |
| PUBMED: | 35152958 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2022 -- Source: Scopus |
