Novel non-protein biomarkers for early detection of hepatocellular carcinoma Review
| Authors: | Abou-Alfa, G. K.; Wu, L.; Villanueva, A. |
| Review Title: | Novel non-protein biomarkers for early detection of hepatocellular carcinoma |
| Abstract: | Early detection of hepatocellular carcinoma (HCC) while in its early stages is critical for reducing HCC mortality in high-risk patients. However, highly sensitive and specific surveillance biomarkers for early-stage HCC detection are still lacking. In recent years, great efforts have been made to research tumor-derived molecular features that are detectable in circulation, such as circulating tumor deoxyribonucleic acid and circulating tumor ribonucleic acid, in order to explore their potential as non-invasive biomarker candidates in many tumor types. In this review, we summarize current studies on these new approaches and their application in early HCC detection. © 2021 THE AUTHORS |
| Keywords: | hepatocellular carcinoma; biomarkers; rna; tumors; early detection; high-risk patients; molecular feature; liquid biopsy; new approaches; 'current |
| Journal Title: | Engineering |
| Volume: | 7 |
| Issue: | 10 |
| ISSN: | 2095-8099 |
| Publisher: | Gaodeng Jiaoyu Chubanshe,Higher Education Press |
| Date Published: | 2021-10-01 |
| Start Page: | 1369 |
| End Page: | 1374 |
| Language: | English |
| DOI: | 10.1016/j.eng.2021.02.020 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 February 2022 -- Source: Scopus |
