Prostate cancer research in the 21st century; Report from the 2021 Coffey-Holden Prostate Cancer Academy Meeting Review


Authors: Miyahira, A. K.; Zarif, J. C.; Coombs, C. C.; Flavell, R. R.; Russo, J. W.; Zaidi, S.; Zhao, D.; Zhao, S. G.; Pienta, K. J.; Soule, H. R.
Review Title: Prostate cancer research in the 21st century; Report from the 2021 Coffey-Holden Prostate Cancer Academy Meeting
Abstract: Introduction: The 2021 Coffey-Holden Prostate Cancer Academy (CHPCA) Meeting, “Prostate Cancer Research in the 21st Century,” was held virtually, from June 24–25, 2021. Methods: The CHPCA Meeting is organized by the Prostate Cancer Foundation as a unique discussion-oriented meeting focusing on critical topics in prostate cancer research envisioned to bridge the next major advances in prostate cancer biology and treatment. The 2021 CHPCA Meeting was virtually attended by 89 investigators and included 31 talks over nine sessions. Results: Major topic areas discussed at the meeting included: cancer genomics and sequencing, functional genomic approaches to studying mediators of plasticity, emerging signaling pathways in metastatic castration resistant prostate cancer, Wnt signaling biology and the challenges of targeted therapy, clonal hematopoiesis, neuroendocrine cell plasticity and antitumor immunity, cancer immunotherapy and its synergizers, and imaging the tumor microenvironment and metabolism. Discussion: This meeting report summarizes the research presented at the 2021 CHPCA Meeting. We hope that publication of this knowledge will accelerate new understandings and the development of new biomarkers and treatments for prostate cancer. © 2021 Wiley Periodicals LLC
Keywords: cancer immunotherapy; molecular imaging; therapeutics; precision medicine; tumor genomics
Journal Title: Prostate
Volume: 82
Issue: 2
ISSN: 0270-4137
Publisher: John Wiley & Sons  
Date Published: 2022-02-01
Start Page: 169
End Page: 181
Language: English
DOI: 10.1002/pros.24262
PROVIDER: scopus
PMCID: PMC8688282
PUBMED: 34734426
DOI/URL:
Notes: Review -- Export Date: 3 January 2022 -- Source: Scopus
Altmetric
Citation Impact
MSK Authors
  1. Samir Zaidi
    7 Zaidi