Current therapeutic options for low-risk papillary thyroid carcinoma: Scoping evidence review Review


Authors: Sanabria, A.; Pinillos, P.; Lira, R. B.; Shah, J. P.; Tufano, R. P.; Zafereo, M. E.; Nixon, I. J.; Randolph, G. W.; Simo, R.; Vander Poorten, V.; Rinaldo, A.; Medina, J. E.; Khafif, A.; Angelos, P.; Mäkitie, A. A.; Shaha, A. R.; Rodrigo, J. P.; Hartl, D. M.; Kowalski, L. P.; Ferlito, A.
Review Title: Current therapeutic options for low-risk papillary thyroid carcinoma: Scoping evidence review
Abstract: Most cases of thyroid carcinoma are classified as low risk. These lesions have been treated with open surgery, remote access thyroidectomy, active surveillance, and percutaneous ablation. However, there is lack of consensus and clear indications for a specific treatment selection. The objective of this study is to review the literature regarding the indications for management selection for low-risk carcinomas. Systematic review exploring inclusion and exclusion criteria used to select patients with low-risk carcinomas for treatment approaches. The search found 69 studies. The inclusion criteria most reported were nodule diameter and histopathological confirmation of the tumor type. The most common exclusions were lymph node metastasis and extra-thyroidal extension. There was significant heterogeneity among inclusion and exclusion criteria according to the analyzed therapeutic approach. Alternative therapeutic approaches in low-risk carcinomas can be cautiously considered. Open thyroidectomy remains the standard treatment against which all other approaches must be compared. © 2021 Wiley Periodicals LLC.
Keywords: treatment; surgery; thyroid carcinoma; papillary carcinoma; surveillance; ablation
Journal Title: Head & Neck
Volume: 44
Issue: 1
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2022-01-01
Start Page: 226
End Page: 237
Language: English
DOI: 10.1002/hed.26883
PUBMED: 34590380
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 3 January 2022 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Jatin P Shah
    722 Shah