Discharge prescribing of enteral opioids in opioid naïve patients following non-surgical intensive care: A retrospective cohort study Journal Article

   

Authors:	Tollinche, L. E.; Seier, K. P.; Yang, G.; Tan, K. S.; Tayban, Y. D.; Pastores, S. M.; Yeoh, C. B.; Karamchandani, K.
Article Title:	Discharge prescribing of enteral opioids in opioid naïve patients following non-surgical intensive care: A retrospective cohort study
Abstract:	Purpose: To estimate the incidence of new prescription of enteral opioids on hospital discharge in opioid naïve, non-surgical, critically ill patients and evaluate the risk factors associated with such occurrence. Methods: Using hospital-wide and ICU databases, we retrospectively identified all patients (≥ 18 years old) who were admitted to the 20-bed adult ICU of Memorial Sloan Kettering Cancer Center (MSKCC) between July 1, 2015 and April 20, 2020. Patients' electronic medical records (EMR) were retrieved and patient demographics, peri-ICU admission data were captured and analyzed. Results: During the study period, a total of 3755 opioid naïve patients were admitted to the ICU and 848 patients met the inclusion criteria. Among these, 346 (40.8%) patients were discharged with a new opioid prescription. Age at ICU admission, preadmission use of benzodiazepine, and antidepressants, a diagnosis of sepsis, and use of mechanical ventilation, antidepressants or, opioid infusion for greater than 4 h during the ICU stay, hospital length of stay (LOS), and days between ICU discharge and hospital discharge were independently associated with increased odds of a new opioid prescription. Conclusions: A significant proportion of opioid naïve non-surgical ICU survivors receive a new opioid prescription on hospital discharge. © 2021
Keywords:	cohort studies; risk factors; patient discharge; analgesics; opioid; critical illness; addiction
Journal Title:	Journal of Critical Care
Volume:	68
ISSN:	0883-9441
Publisher:	W.B. Saunders Co.
Date Published:	2022-04-01
Start Page:	16
End Page:	21
Language:	English
DOI:	10.1016/j.jcrc.2021.10.021
PROVIDER:	scopus
PUBMED:	34856489
PMCID:	PMC9473333
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85120990717&doi=10.1016%2fj.jcrc.2021.10.021&partnerID=40&md5=6c491b68aa4378a65a5dec3b678aad03
Notes:	Article -- Export Date: 3 January 2022 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/191695