Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas Review


Authors: Fujiwara, T.; Ogura, K.; Christ, A.; Bartelstein, M.; Kenan, S.; Fabbri, N.; Healey, J.
Review Title: Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas
Abstract: Limb-salvage surgery for pelvic sarcomas remains one of the most challenging surgical procedures for musculoskeletal oncologists. In the past several decades, various surgical techniques have been developed for periacetabular reconstruction following pelvic tumor resection. These methods include endoprosthetic reconstruction, allograft or autograft reconstruction, arthrodesis, and hip transposition. Each of these procedures has its own advantages and disadvantages, and there is no consensus or gold standard for periacetabular reconstruction. Consequently, this review provides an overview of the clinical outcomes for each of these reconstructive options following pelvic tumor resections. Overall, high complication rates are associated with the use of massive implants/grafts, and deep infection is generally the most common cause of reconstruction failure. Functional outcomes decline with the occurrence of severe complications. Further efforts to avoid complications using innovative techniques, such as antibiotic-laden devices, computer navigation, custom cutting jigs, and reduced use of implants/grafts, are crucial to improve outcomes, especially in patients at a high risk of complications. © 2021 The Authors
Keywords: cancer surgery; limb salvage; treatment failure; review; pelvis; sarcoma; irradiation; surgical infection; reconstruction; pelvis cancer; pelvis surgery; bone allograft; clinical outcome; freezing; arthrodesis; acetabulum; hip surgery; human; limb-salvage; pasteurization; periacetabular reconstruction
Journal Title: Journal of Bone Oncology
Volume: 31
ISSN: 2212-1374
Publisher: Elsevier Inc.  
Date Published: 2021-12-01
Start Page: 100396
Language: English
DOI: 10.1016/j.jbo.2021.100396
PROVIDER: scopus
PMCID: PMC8577502
PUBMED: 34786331
DOI/URL:
Notes: Review -- Export Date: 1 December 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. John H Healey
    547 Healey
  2. Nicola Fabbri
    64 Fabbri
  3. Shachar Kenan
    4 Kenan
  4. Alexander Bryant Christ
    11 Christ
  5. Koichi Ogura
    15 Ogura