The association between patient health status and surrogate decision maker post-traumatic stress disorder symptoms in chronic critical illness Journal Article


Authors: Wendlandt, B.; Ceppe, A.; Cox, C. E.; Hanson, L. C.; Nelson, J. E.; Carson, S. S.
Article Title: The association between patient health status and surrogate decision maker post-traumatic stress disorder symptoms in chronic critical illness
Abstract: Rationale: Surrogate decision-makers of patients with chronic critical illness (CCI) are at high risk for symptoms of posttraumatic stress disorder (PTSD). Whether patient health status after hospital discharge is a risk factor for surrogate PTSD symptoms is not known. Objectives: To determine the association between patient health status 90 days after the onset of CCI and surrogate symptoms of PTSD. Methods: We performed a secondary analysis of the data from a multicenter randomized trial of a communication intervention for adult patients with CCI and their surrogate decision-makers. Results: Surrogate PTSD symptoms were measured at 90 days using the Impact of Events Scale–Revised. For patients who were alive at 90 days, location was used as a marker of health status and included the following categories: 1) home (relatively good health and low acuity), 2) acute rehabilitation (moderate care needs and impairments, generally expected to improve), 3) skilled nursing facility (moderate care needs and impairments, generally not expected to improve significantly or quickly), 4) long-term acute care facility (persistently high acute care needs and functional impairment), and 5) readmission to an acute care hospital (suggesting the highest acuity of illness and care needs of the cohort). Patients who died before 90 days were categorized as deceased. In the analyses, 365 surrogates and 256 patients were included. Among patients, 49% were female, and the mean age was 59 years. Among surrogates, 71% were female, and the mean age was 51 years. A directed acyclic graph was constructed to identify covariates to be included in the model. Compared with symptoms seen among surrogates of patients living at home, heightened PTSD symptoms were seen among surrogates of patients who were readmitted to an acute care hospital (b coefficient, 15.9; 95% confidence interval [CI], 4.5 to 27.3) or had died (b coefficient, 14.8; 95% CI, 8.8 to 20.9) at 90 days. Conclusions: Surrogates of patients with CCI who have died or have been readmitted to an acute care hospital at 90 days experience increased PTSD symptoms as compared with surrogates of patients who are living at home. These patients and surrogates represent a readily identifiable group who may benefit from enhanced emotional support. © 2021 by the American Thoracic Society
Keywords: adult; controlled study; middle aged; major clinical study; outcome assessment; follow up; randomized controlled trial; cohort analysis; risk factor; confidence interval; chronic disease; intensive care unit; symptom; correlation analysis; health status; multicenter study; posttraumatic stress disorder; predictor variable; caregiver; emergency care; high risk population; hospital readmission; home care; decision making; rehabilitation care; critical illness; nursing home; secondary analysis; impact of events scale; functional disease; health care need; post-traumatic stress disorder; family caregiver; human; male; female; article; chronic critical illness; minimal clinically important difference; surrogate decision maker; directed acyclic graph
Journal Title: Annals of the American Thoracic Society
Volume: 18
Issue: 11
ISSN: 2329-6933
Publisher: American Thoracic Society  
Date Published: 2021-11-01
Start Page: 1868
End Page: 1875
Language: English
DOI: 10.1513/AnnalsATS.202010-1300OC
PROVIDER: scopus
PUBMED: 33794122
PMCID: PMC8641832
DOI/URL:
Notes: Article -- Export Date: 1 December 2021 -- Source: Scopus
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  1. Judith Eve Nelson
    89 Nelson