The temperature dependence of cellular radiation sensitivity as a method of investigating mechanisms of inactivation Journal Article


Authors: Weiss, H.; Strauss, A.; Lee, R.
Article Title: The temperature dependence of cellular radiation sensitivity as a method of investigating mechanisms of inactivation
Abstract: Bacteria, at temperatures in the range from 6°C to 43°C, were exposed to intense pulses of 450 keV electrons from a field emission accelerator or to cyclotron-produced 24 MeV 3He++ particles degraded by 0.025 mm or by 0.15 mm thick aluminium foils. The bacteria were plated in thin aqueous layers on membrane filters for all of the irradiations and equilibrated with humidified gases. For the irradiations by electrons, with cells in nitrogen, survival decreased with increasing temperature over the whole range. A similar response was measured for cells in nitrogen or air that were exposed to 3He++ particles degraded by the thicker foil. There was no temperature dependence with the thinner foil. These results can be interpreted as a demonstration that different processes are involved in the inactivation of cells; one of these may be a cooperative type of interaction.
Keywords: nonhuman; methodology; in vitro study; radiosensitivity; temperature; bacterium; beta radiation; helium ion radiation
Journal Title: Radiation Protection Dosimetry
Volume: 13
Issue: 1-4
ISSN: 0144-8420
Publisher: Oxford University Press  
Date Published: 1985-12-01
Start Page: 181
End Page: 184
Language: English
DOI: 10.1093/oxfordjournals.rpd.a079574
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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  1. Herbert Weiss
    3 Weiss