Authors: | Matulic-Adamic, J.; Watanabe, K. A. |
Article Title: | Synthesis of 2′-deoxy-5-monofluoromethyluridine (FTDR) and 2′-deoxy-5-difluoromethyluridine (F2TDR) |
Abstract: | The synthesis of potential anticancer and antitumour nucleosides, 2′-deoxy-5-monofluoromethyluridine (FTDR) and 2′-deoxy-5-difluoromethyluridine (F2TDR) was achieved in four steps from thymidine including monosilylation with t-butyldiphenylsilyl chloride, photochemical bromination, followed by AgF treatment and subsequent desilylation. © 1985 The Royal Society of Chemistry, All rights reserved. |
Journal Title: | Journal of the Chemical Society, Chemical Communications |
Volume: | 1985 |
Issue: | 21 |
ISSN: | 0022-4936 |
Publisher: | Royal Society of Chemistry |
Date Published: | 1985-11-01 |
Start Page: | 1535 |
End Page: | 1536 |
Language: | English |
DOI: | 10.1039/c39850001535 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |