Synthesis of 2′-deoxy-5-monofluoromethyluridine (FTDR) and 2′-deoxy-5-difluoromethyluridine (F2TDR) Journal Article


Authors: Matulic-Adamic, J.; Watanabe, K. A.
Article Title: Synthesis of 2′-deoxy-5-monofluoromethyluridine (FTDR) and 2′-deoxy-5-difluoromethyluridine (F2TDR)
Abstract: The synthesis of potential anticancer and antitumour nucleosides, 2′-deoxy-5-monofluoromethyluridine (FTDR) and 2′-deoxy-5-difluoromethyluridine (F2TDR) was achieved in four steps from thymidine including monosilylation with t-butyldiphenylsilyl chloride, photochemical bromination, followed by AgF treatment and subsequent desilylation. © 1985 The Royal Society of Chemistry, All rights reserved.
Journal Title: Journal of the Chemical Society, Chemical Communications
Volume: 1985
Issue: 21
ISSN: 0022-4936
Publisher: Royal Society of Chemistry  
Date Published: 1985-11-01
Start Page: 1535
End Page: 1536
Language: English
DOI: 10.1039/c39850001535
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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