The role of paraaortic node irradiation in the treatment of cancer of the cervix Journal Article


Authors: Nori, D.; Valentine, E.; Hilaris, B. S.
Article Title: The role of paraaortic node irradiation in the treatment of cancer of the cervix
Abstract: One hundred and twenty-seven patients with previously untreated carcinoma of the uterine cervix underwent pretreatment laparotomy between 1971 and 1980. Thirty-one were found to have paraaortic metastasis. Twenty-seven patients received paraaortic node external supervoltage radiation to the entire paraaortic chain, 4400 cGy, over 4 1 2 weeks, with 600-800 cGy, boost over 1 week, limited to the area of metastasis as marked at laparotomy. Twenty-nine percent ( 8 27) of the patients with paraaortic node metastases who were irradiated have survived 5 years or more. These patients have FIGO stages IB IIA, or IIB; all have epidermoid carcinoma. Three of five patients (60%) with microscopic metastasis and five of twenty-two patients (23%) with gross metastasis in the paraaortic lymph nodes are long-term survivors. None of our long-term survivors have suffered late complications. There have been no fatalities from treatment related complications. We present a radiation technique for paraaortic radiation in these patients, and discuss the indications for paraaortic node radiation in cancer of the cervix. © 1985.
Keywords: major clinical study; carcinoma, squamous cell; lymph node metastasis; paraaortic lymph node; lymph nodes; lymphatic metastasis; radiotherapy; lymphatic system; diagnosis; therapy; uterine cervix carcinoma; female genital system; aorta; cervix neoplasms; prognosis; human; female; priority journal; carcinoma of the cervix; paraaortic nodal irradiation; pretreatment laparotomy
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 11
Issue: 8
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1985-08-01
Start Page: 1469
End Page: 1473
Language: English
DOI: 10.1016/0360-3016(85)90334-7
PUBMED: 4019270
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Basil B Hilaris
    43 Hilaris
  2. Dattatreyudu Nori
    38 Nori