Potential use of human interleukin 2 as an adjunct for the therapy of neoplasia, immunodeficiency and infectious disease Journal Article
| Authors: | Merluzzi, V. J.; Last-Barney, K. |
| Article Title: | Potential use of human interleukin 2 as an adjunct for the therapy of neoplasia, immunodeficiency and infectious disease |
| Abstract: | Experimental and clinical systems have been developed to analyze both the in vitro and in vivo effects of highy purified interleukin 2 (IL2) as a potential therapeutic adjunct for neoplasia, immunodeficiency and infectious disease. Animal models, clinical in vitro studies, as well as preliminary clinical trials of IL2 in vivo show that this lymphokine may provide a necessary signal for the activation of thymus-derived T cells in immunologically-compromised hosts. © 1985. |
| Keywords: | review; nonhuman; neoplasms; t lymphocyte; animal; mice; interleukin 2; cancer immunotherapy; infection; animal model; killer cells, natural; immune deficiency; drug therapy; bone marrow transplantation; immunologic deficiency syndromes; therapy; clinical trials; interleukin-2; immunity, cellular; cancer; human; priority journal; support, u.s. gov't, p.h.s. |
| Journal Title: | International Journal of Immunopharmacology |
| Volume: | 7 |
| Issue: | 1 |
| ISSN: | 0192-0561 |
| Publisher: | Elsevier Ltd |
| Date Published: | 1985-01-01 |
| Start Page: | 31 |
| End Page: | 39 |
| Language: | English |
| DOI: | 10.1016/0192-0561(85)90006-2 |
| PUBMED: | 3888867 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
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