Phase II trial of gallium nitrate in patients with advanced malignant melanoma Journal Article
| Authors: | Casper, E. S.; Stanton, G. F.; Sordillo, P. P.; Parente, R.; Michaelson, R. A.; Vinceguerra, V. |
| Article Title: | Phase II trial of gallium nitrate in patients with advanced malignant melanoma |
| Abstract: | A phase II trial of gallium nitrate (250-300 mg/m2/day for 7 consecutive days) was conducted in patients with metastatic melanoma. Therapy was well-tolerated, but only one of 31 evaluable patients experienced a partial regression. Further evaluation of gallium nitrate at this dose and schedule is not warranted in patients with malignant melanoma. |
| Keywords: | adult; cancer chemotherapy; clinical article; aged; middle aged; drug efficacy; melanoma; nephrotoxicity; phase 2 clinical trial; skin neoplasms; nausea; vomiting; calcium; creatinine; creatinine blood level; gastrointestinal toxicity; kidney; neoplasm metastasis; radioisotope; drug therapy; gallium citrate ga 67; adverse drug reaction; therapy; infusions, parenteral; intravenous drug administration; fluid retention; hypocalcemia; abdominal neoplasms; gallium; drug evaluation; intoxication; electrolytes; dose kidney function relation; gallium nitrate; cancer; humans; human; male; female; priority journal |
| Journal Title: | Cancer Treatment Reports |
| Volume: | 69 |
| Issue: | 9 |
| ISSN: | 0361-5960 |
| Publisher: | National Cancer Institute |
| Date Published: | 1985-09-01 |
| Start Page: | 1019 |
| End Page: | 1020 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 4028034 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
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