Seventh-day Adventist vegetarians have a quiescent proliferative activity in colonic mucosa Journal Article

  


Authors: Lipkin, M.; Uehara, K.; Winawer, S.; Sanchez, A.; Bauer, C.; Phillips, R.; Lynch, H. T.; Blattner, W. A.; Fraumeni, J. F. Jr
Article Title: Seventh-day Adventist vegetarians have a quiescent proliferative activity in colonic mucosa
Abstract: The proliferation of epithelial cells in colonic mucosa was studied in humans at varying degrees of risk for colon cancer. Seventh-Day Adventist vegetarians, known to have significantly lower mortality from colon cancer than the general U.S. population, had the most quiescent proliferative activity of mucosal epithelial cells. Increased replication and expansion of the proliferative compartment accompanied increased colon cancer risk. The analytical methods of this study may be useful in assessing the influence of dietary components involved in the initiation, promotion or inhibition of colon cancer, and in developing strategies for nutritional intervention. © 1985.
Keywords: adult; middle aged; human cell; cancer risk; cell proliferation; cell division; colonic neoplasms; risk; radioisotope; colon; cytokinesis; etiology; colon mucosa; intestinal mucosa; large intestine; diet, vegetarian; humans; human; male; female; christianity; vegetarian
Journal Title: Cancer Letters
Volume: 26
Issue: 2
ISSN: 0304-3835
Publisher: Elsevier Ireland Ltd.  
Date Published: 1985-03-01
Start Page: 139
End Page: 144
Language: English
DOI: 10.1016/0304-3835(85)90019-9
PUBMED: 3978603
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021949646&doi=10.1016%2f0304-3835%2885%2990019-9&partnerID=40&md5=c5866acd4d0a6c703a94bbd74d2839fb
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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MSK Authors
  1. Sidney J Winawer
    276 Winawer
  2. Martin Lipkin
    116 Lipkin
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