Experimental studies and phase II trial of bisantrene in advanced urothelial malignancies Journal Article
| Authors: | Scher, H. I.; Ahmed, T.; Yagoda, A.; Kyriazis, A. P.; Watson, R. C. |
| Article Title: | Experimental studies and phase II trial of bisantrene in advanced urothelial malignancies |
| Abstract: | A phase II trial with bisantrene was performed simultaneously against urothelial tumors in nude mice and in patients with metastatic transitional cell carcinoma. The starting dose was 260 mg/m2, intravenously, every 3 weeks. No responses were seen in the in vivo animal study or in 13 treated patients. © 1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
| Keywords: | cancer chemotherapy; clinical article; aged; middle aged; antibiotic agent; chemotherapy; mouse; animals; mice; metastasis; phase 2 clinical trial; bone marrow; transplantation; urinary bladder neoplasms; mice, inbred balb c; chill; fever; hypotension; nude mouse; cardiovascular system; drug therapy; carcinoma, transitional cell; antibiotics, antineoplastic; bladder carcinoma; adverse drug reaction; therapy; urinary tract; infusion fluid; intravenous drug administration; phlebitis; bladder; bone marrow depression; drug evaluation; bisantrene; anthracenes; cancer; humans; human; male; female; blood and hemopoietic system; peripheral vascular system |
| Journal Title: | Cancer Investigation |
| Volume: | 3 |
| Issue: | 2 |
| ISSN: | 0735-7907 |
| Publisher: | Informa Healthcare |
| Date Published: | 1985-01-01 |
| Start Page: | 123 |
| End Page: | 127 |
| Language: | English |
| DOI: | 10.3109/07357908509017495 |
| PUBMED: | 3995377 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
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25Caird Watson
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