Soft tissue sarcomas of the hand and foot Journal Article

  


Authors: Owens, J. C.; Shiu, M. H.; Smith, R.; Hajdu, S. I.
Article Title: Soft tissue sarcomas of the hand and foot
Abstract: A retrospective study was made of 82 soft tissue sarcomas of the hand and foot. Prognosis was related to histopathologic grade of malignancy and success or failure of local tumor control. After treatment with curative intent, low‐grade tumors gave a 5‐year survival rate of 90%, compared to 63% for high‐grade tumors. Simple excision or limited amputation of the digit, hand, or foot yielded a 5‐year survival rate of 68% (15/22) and a local recurrence rate of 32%. Amputation below the elbow or knee or higher resulted in a similar survival of 68% (19/28) but no local recurrences. All patients who developed local recurrences died, except for two with low‐grade tumors and one patient lost to follow‐up. These observations indicate the need for systemic chemotherapy to prevent death from metastasis, and for effective local tumor control. Conventional radiation therapy may be difficult to apply at these sites. Innovative local treatment approaches to preserve limb function without jeopardizing tumor control merit study. Copyright © 1985 American Cancer Society
Keywords: adolescent; adult; child; aged; child, preschool; major clinical study; histopathology; chemotherapy; neoplasm recurrence, local; radiotherapy; time factors; sarcoma; soft tissue; diagnosis; neoplasm metastasis; amputation; soft tissue sarcoma; neoplasm invasiveness; therapy; soft tissue neoplasms; foot; hand; middle age; prognosis; human; male; female; priority journal; foot cancer; hand cancer
Journal Title: Cancer
Volume: 55
Issue: 9
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1985-05-01
Start Page: 2010
End Page: 2018
Language: English
DOI: 10.1002/1097-0142(19850501)55:9<2010::Aid-cncr2820550931>3.0.Co;2-w
PUBMED: 3978581
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0021925826&doi=10.1002%2f1097-0142%2819850501%2955%3a9%3c2010%3a%3aAID-CNCR2820550931%3e3.0.CO%3b2-W&partnerID=40&md5=4c0efa5e4c24150df96dd4874041ad0b
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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MSK Authors
  1. Steven I. Hajdu
    80 Hajdu
  2. Man-Hei Shiu
    44 Shiu
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