Salmonella infections in patients with the acquired immunodeficiency syndrome Journal Article


Authors: Jacobs, J. L.; Gold, J. W. M.; Murray, H. W.; Roberts, R. B.; Armstrong, D.
Article Title: Salmonella infections in patients with the acquired immunodeficiency syndrome
Abstract: Defects in T cell function have been seen in patients with the acquired immunodeficiency syndrome. Although the cellular immune system plays a key role in host defense against Salmonella, there have no detailed reports of salmonellosis in patients with this syndrome. We report our experience with salmonella infections in six patients. Salmonellosis in these patients was unusually severe, characterized by widespread infection, bacteremia, and relapse, despite standard antibiotic treatment. Because of the difficulty in eradicating salmonella infection in patients with the acquired immunodeficiency syndrome, long-term suppressive treatment with antibiotics seems warranted.
Keywords: prednisone; case report; drug resistance; salmonellosis; bacteremia; acquired immune deficiency syndrome; gentamicin; drug therapy; small intestine; cotrimoxazole; drug sensitivity; therapy; amoxicillin; ampicillin; minimum inhibitory concentration; reticuloendothelial system; large intestine; chloramphenicol; fiacitabine; human; priority journal; cefoxitin; blood and hemopoietic system
Journal Title: Annals of Internal Medicine
Volume: 102
Issue: 2
ISSN: 0003-4819
Publisher: American College of Physicians  
Date Published: 1985-02-01
Start Page: 186
End Page: 188
Language: English
DOI: 10.7326/0003-4819-102-2-186
PROVIDER: scopus
PUBMED: 3881072
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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  1. Donald Armstrong
    240 Armstrong
  2. Jonathan W. M. Gold
    73 Gold