Current considerations for radiotherapy in HPV-associated head and neck cancer Review


Authors: Chen, L.; Riaz, N.; Lee, N.; McBride, S.
Review Title: Current considerations for radiotherapy in HPV-associated head and neck cancer
Abstract: Human papillomavirus (HPV)-mediated oncogenesis confers increased sensitivity to radiotherapy and HPV head and neck cancer is associated with improved patient outcomes. As such, management of HPV-related head and neck cancer requires a multidisciplinary approach that balances maximizing locoregional control with minimizing treatment-related toxicity. We highlight considerations in radiation dose and target delineation, as well as considerations for chemoradiation, postoperative radiotherapy, and single modality, definitive radiotherapy. © 2021 Wiley Periodicals LLC
Keywords: radiotherapy; human papillomavirus; definitive chemoradiation
Journal Title: Journal of Surgical Oncology
Volume: 124
Issue: 6
ISSN: 0022-4790
Publisher: Wiley Blackwell  
Date Published: 2021-11-01
Start Page: 945
End Page: 951
Language: English
DOI: 10.1002/jso.26689
PROVIDER: scopus
PUBMED: 34617275
DOI/URL:
Notes: Review -- Source: Scopus
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  1. Nadeem Riaz
    415 Riaz
  2. Nancy Y. Lee
    871 Lee
  3. Sean Matthew McBride
    293 McBride
  4. Linda Chang Chen
    67 Chen