Artificial intelligence in thyroid fine needle aspiration biopsies Review


Authors: Kezlarian, B.; Lin, O.
Review Title: Artificial intelligence in thyroid fine needle aspiration biopsies
Abstract: Background: From cell phones to aerospace, artificial intelligence (AI) has wide-reaching influence in the modern age. In this review, we discuss the application of AI solutions to an equally ubiquitous problem in cytopathology - thyroid fine needle aspiration biopsy (FNAB). Thyroid nodules are common in the general population, and FNAB is the sampling modality of choice. The resulting prevalence in the practicing pathologist's daily workload makes thyroid FNAB an appealing target for the application of AI solutions. Summary: This review summarizes all available literature on the application of AI to thyroid cytopathology. We follow the evolution from morphometric analysis to convolutional neural networks. We explore the application of AI technology to different questions in thyroid cytopathology, including distinguishing papillary carcinoma from benign, distinguishing follicular adenoma from carcinoma and identifying non-invasive follicular thyroid neoplasm with papillary-like nuclear features by key words and phrases. Key Messages: The current literature shows promise towards the application of AI technology to thyroid fine needle aspiration biopsy. Much work is needed to define how this powerful technology will be of best use to the future of cytopathology practice. © 2020 The Author(s) Published by S. Karger AG, Basel.
Keywords: reproducibility; reproducibility of results; image interpretation, computer-assisted; diagnosis, differential; differential diagnosis; pathology; computer assisted diagnosis; artificial intelligence; biopsy, fine-needle; predictive value of tests; thyroid neoplasms; thyroid tumor; predictive value; diagnosis, computer-assisted; fine needle aspiration biopsy; machine learning; humans; human; neural networks, computer; thyroid fine needle aspiration biopsy
Journal Title: Acta Cytologica
Volume: 65
Issue: 4
ISSN: 0001-5547
Publisher: S. Karger AG  
Date Published: 2021-07-01
Start Page: 324
End Page: 329
Language: English
DOI: 10.1159/000512097
PUBMED: 33326953
PROVIDER: scopus
PMCID: PMC8491503
DOI/URL:
Notes: Review -- Export Date: 1 October 2021 -- Source: Scopus
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  1. Oscar Lin
    310 Lin