Preliminary effects of low-intensity focused ultrasound treatment program for cancer-related neuropathic pain Journal Article


Authors: Patel, A. A.; Zhukosvky, M.; Sidharthan, S.; Jotwani, R.; Rakesh, N.; Gulati, A.
Article Title: Preliminary effects of low-intensity focused ultrasound treatment program for cancer-related neuropathic pain
Abstract: Aim: To evaluate the effectiveness of low-intensity focused ultrasound (LIFU) therapy in the management of cancer-related neuropathic pain (CNP). Methods: A retrospective review with 22 patients with CNP treated with LIFU therapy (frequency 3 Hz, 3 W/cm2, pulse mode duty cycle 50%) was conducted. Results: Out of the 22 patients, 15 had CNP secondary to chemotherapy-induced peripheral neuropathy. Compared with baseline, there was a significant reduction in numeric pain rating scale (p < 0.001). Additionally, 76.5% of patients (n = 13) were considered to be responders to LIFU therapy. Conclusion: LIFU therapy may be a viable treatment modality in the management of CNP, specifically chemotherapy-induced peripheral neuropathy, with a minimal side effect profile. Larger, prospective studies with a structured protocol are necessary. © 2021 Future Medicine Ltd.
Keywords: malignancy; neuropathic pain; chemotherapy-induced peripheral neuropathy; cancer-related pain; therapeutic ultrasound; low-intensity focused ultrasound
Journal Title: Pain Management
Volume: 11
Issue: 5
ISSN: 1758-1869
Publisher: Future Medicine  
Date Published: 2021-09-01
Start Page: 613
End Page: 621
Language: English
DOI: 10.2217/pmt-2020-0099
PUBMED: 34102872
PROVIDER: scopus
PMCID: PMC9344434
DOI/URL:
Notes: Article -- Export Date: 1 September 2021 -- Source: Scopus
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  1. Amitabh Gulati
    146 Gulati