Intraluminal radiation therapy in the management of malignant biliary obstruction Conference Paper
| Authors: | Molt, P.; Hopfan, S.; Watson, R. C.; Botet, J. F.; Brennan, M. F. |
| Title: | Intraluminal radiation therapy in the management of malignant biliary obstruction |
| Conference Title: | 38th Annual Meeting of the Surgical Oncology |
| Abstract: | Fifteen patients with maligant biliary obstruction from carcinoma of the bile ducts, gallbladder, and pancreas (Group I) or metastatic disease (Group II) were treated with intraluminal radiation therapy (ILRT) at Memorial Sloan‐Kettering Cancer Center. In 11 cases ILRT was used as a central boost in combination with 3000 cGy external beam radiation therapy (ERT). No significant treatment toxicity was observed. Cholangiographic response was observed in 2 of 12 evaluable patients. In no patient was long‐term relief of jaundice without indwelling biliary stent achieved. Survival from treatment in eight Group I patients treated with ILRT ± ERT was 3 to 13 months (median, 4.5). Survival in seven similarly treated Group II patients was 0.5 to 8 months (median, 4.0). Additional data for ten similiar patients referred for ILRT but treated with ERT alone are presented. Analysis of this and other reports indicate the need for prospective controlled trials of the role of this regimen in the management of malignant biliary obstruction before wider application can be recommended. Copyright © 1986 American Cancer Society |
| Keywords: | adolescent; adult; clinical article; aged; middle aged; pancreatic neoplasms; pancreas; metastasis; radiotherapy dosage; radiotherapy; pancreas carcinoma; brachytherapy; bile duct carcinoma; bile duct neoplasms; bile duct obstruction; gallbladder carcinoma; gallbladder neoplasms; radioisotopes; therapy; cholestasis; bile duct; iridium; gallbladder; humans; human; male; female; priority journal |
| Journal Title | Cancer |
| Volume: | 57 |
| Issue: | 3 |
| Conference Dates: | 1985 May 19-22 |
| Conference Location: | Houston, TX |
| ISBN: | 0008-543X |
| Publisher: | Wiley Blackwell |
| Date Published: | 1986-02-01 |
| Start Page: | 536 |
| End Page: | 544 |
| Language: | English |
| DOI: | 10.1002/1097-0142(19860201)57:3<536::Aid-cncr2820570322>3.0.Co;2-l |
| PUBMED: | 3942986 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 18 August 2021 -- Source: Scopus; Acknowledgments: The authors thank Lowell Anderson, PhD who performed the dosimetry calculations. |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
-
1059Brennan -
60Botet -
2Hopfan -
25Caird Watson
Related MSK Work