Treatment of acute obstructive renal failure with high-dose methylprednisolone Journal Article

  


Authors: Flombaum, C. D.; Schroy, P.; Watson, R.; Vanamee, P.
Article Title: Treatment of acute obstructive renal failure with high-dose methylprednisolone
Abstract: • High-dose methylprednisolone sodium succinate (Solu-Medrol) therapy was administered to two patients with acute renal failure and anuria secondary to cancer-related urinary tract obstruction. Following the administration of intravenous methylprednisolone, obstruction was relieved, as evidenced by increased urinary flow and improvement of renal function. The salutary effect of methylprednisolone is probably related to the relief of obstruction secondary to a decrease in tumorassociated edema similar to the effect obtained in patients with brain tumors and spinal cord compression by epidural metastases. The temporary improvement in renal function allowed time for more definitive therapy to be instituted under more favorable clinical conditions. © 1986, American Medical Association. All rights reserved.
Keywords: aged; case report; drug efficacy; edema; hodgkin disease; acute kidney failure; kidney; diagnosis; insulin; glucose; methylprednisolone; radioisotope; drug therapy; therapy; urinary tract; intravenous drug administration; injections, intravenous; drug indication; urinary tract obstruction; kidney failure, acute; cervix neoplasms; ureteral obstruction; bicarbonate; methylprednisolone sodium succinate; polystyrenesulfonate sodium; anuria; cancer; human; male; female; priority journal; methylprednisolone hemisuccinate
Journal Title: Archives of Internal Medicine
Volume: 146
Issue: 1
ISSN: 0003-9926
Publisher: American Medical Association  
Date Published: 1986-01-01
Start Page: 58
End Page: 61
Language: English
DOI: 10.1001/archinte.1986.00360130068009
PUBMED: 3510599
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022587287&doi=10.1001%2farchinte.1986.00360130068009&partnerID=40&md5=ce6edaf7d74cd6ac0fce87e8771aae57
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Carlos D Flombaum
    53 Flombaum
  2. Paul C. Schroy
    12 Schroy
  3. Robin Caird Watson
    25 Caird Watson
Related MSK Work