The purely epithelioid malignant peripheral nerve sheath tumor Journal Article


Authors: DiCarlo, E. F.; Woodruff, J. M.; Bansal, M.; Erlandson, R. A.
Article Title: The purely epithelioid malignant peripheral nerve sheath tumor
Abstract: The purely epithelioid malignant peripheral nerve sheath tumor (PNST) is a rare form of PNT possibly first described by McCormack et al. in 1954. This tumor type is distinguishable from the glandular PNT and PNT with differentiated neuroepithelium (medulloepithelioma and neuroepithelioma) and differs from the ordinary epithelioid PNT because of the absence of a spindle cell component typical of malignant PNSTs. The two examples of purely epithelioid malignant PNT we describe arose in the popliteal fossa from the sciatic and tibial nerves of men with no definite evidence of von Recklinghausen's neurofibromatosis. Both tumors were partly mucinous, and so closely mimicked carcinoma and a few non-neurogenic myxoid sarcomas histologically that their final classification depended upon proof of a neural origin.
Keywords: immunohistochemistry; histopathology; case report; cytology; electron microscopy; histology; diagnosis; protein s 100; nerve sheath tumor; epithelioid sarcoma; ultrastructure; peripheral nervous system; nervous system; nerve tumor; human; priority journal; neurofibrosarcoma
Journal Title: American Journal of Surgical Pathology
Volume: 10
Issue: 7
ISSN: 0147-5185
Publisher: Lippincott Williams & Wilkins  
Date Published: 1986-07-01
Start Page: 478
End Page: 490
Language: English
DOI: 10.1097/00000478-198607000-00005
PUBMED: 2425646
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus
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  1. James M Woodruff
    162 Woodruff
  2. Robert A Erlandson
    125 Erlandson