Which botanicals or other unconventional anticancer agents should we take to clinical trial? Journal Article
| Author: | Vickers, A. J. |
| Article Title: | Which botanicals or other unconventional anticancer agents should we take to clinical trial? |
| Abstract: | There is significant public and scientific interest as regards unconventional anticancer agents (complementary and alternative medicine [CAM] agents). This article describes five principles pertaining to the question of which CAM agents should be taken to clinical trial: (1) many CAM agents have been proposed as cancer treatments, far more than could possibly be studied in clinical trials; (2) claims by patients or practitioners are generally unhelpful in choosing which CAM agents to test; (3) laboratory studies can help determine which CAM agents to take to trial and with which cointerventions; (4) preliminary laboratory studies are essential to confirm safety before trials can be considered; and (5) the vast majority of anticancer CAM agents will be ineffective; our aim should be to discard agents from consideration as rapidly as possible. |
| Keywords: | clinical trial; review; drug safety; clinical trials as topic; antineoplastic agent; neoplasms; antineoplastic agents, phytogenic; cancer therapy; patient participation; laboratory test; physician; alternative medicine; complementary therapies; antioxidants; dietary supplements; botanicals; medicine, herbal; plants, medicinal; herb-drug interactions; herbs; botany |
| Journal Title: | Journal of the Society for Integrative Oncology |
| Volume: | 5 |
| Issue: | 3 |
| ISSN: | 1715-894X |
| Publisher: | BC Decker |
| Date Published: | 2007-06-01 |
| Start Page: | 125 |
| End Page: | 129 |
| Language: | English |
| DOI: | 10.2310/7200.2007.011 |
| PUBMED: | 17761132 |
| PROVIDER: | scopus |
| PMCID: | PMC2590766 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "Source: Scopus" |
