Radioactive iodine therapy in poorly differentiated thyroid cancer Journal Article
| Authors: | Tuttle, R. M.; Grewal, R. K.; Larson, S. M. |
| Article Title: | Radioactive iodine therapy in poorly differentiated thyroid cancer |
| Abstract: | Background: A 55-year-old male was diagnosed with poorly differentiated thyroid cancer after total thyroidectomy, which was performed because of progressive enlargement of a dominant thyroid nodule. He developed an early cervical recurrence that was treated with modified neck dissection. He subsequently developed biopsy-proven progressive pulmonary metastases. Investigations: Neck and chest CT scans, laboratory tests, CT-guided fine-needle aspiration biopsy, [18F]-2-fluoro-2-deoxy-D- glucose-PET scan, lesional dosimetry using 124I PET scan, diagnostic radioactive iodine (RAI) scanning, whole-body and blood RAI dosimetry, and single-photon-emission CT. Diagnosis: Stage IV poorly differentiated thyroid cancer. Management: Surgical resection of cervical recurrence, RAI therapy. |
| Keywords: | adult; human tissue; middle aged; cancer recurrence; case report; neck dissection; postoperative period; positron emission tomography; follow up; lymph node metastasis; lymph node dissection; neoplasm staging; radiopharmaceuticals; computer assisted tomography; neoplasm recurrence, local; diagnosis, differential; lung neoplasms; tumor differentiation; lung metastasis; iodine 131; radioactive iodine; iodine radioisotopes; fluorodeoxyglucose f 18; carcinoma; neoplasm metastasis; thyroidectomy; iodine 124; thyroid cancer; thyroid neoplasms; aspiration biopsy; thyroid nodule; single photon emission computer tomography; lung biopsy; treatment refusal; radioisotope therapy; nodular goiter; neck metastasis; thyroid scintiscanning |
| Journal Title: | Nature Clinical Practice Oncology |
| Volume: | 4 |
| Issue: | 11 |
| ISSN: | 1743-4254 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2007-11-01 |
| Start Page: | 665 |
| End Page: | 668 |
| Language: | English |
| DOI: | 10.1038/ncponc0979 |
| PUBMED: | 17965644 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 6" - "Export Date: 17 November 2011" - "Source: Scopus" |
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