Are we still scratching the surface? A case of intractable pruritus following systemic opioid analgesia Journal Article
| Authors: | Tarcatu, D.; Tamasdan, C.; Moryl, N.; Obbens, E. |
| Article Title: | Are we still scratching the surface? A case of intractable pruritus following systemic opioid analgesia |
| Abstract: | This article describes a case of severe opioid-induced pruritus following systemic morphine administration. Symptoms did not resolve after administration of antihistamines or rotation to fentanyl or hydromorphone, but oral oxycodone and small-dose intravenous naloxone did alleviate the patient's itching. The pathogenesis of opioid-induced pruritus and the rationale for opioid rotation are briefly discussed. Current and possible future therapeutic options are mentioned. |
| Keywords: | adolescent; cancer chemotherapy; acute granulocytic leukemia; case report; drug withdrawal; cancer radiotherapy; pain; mucosa inflammation; nausea; vomiting; vincristine; continuous infusion; febrile neutropenia; pruritus; symptom; narcotic analgesic agent; disease severity; pelvis tumor; hospital admission; morphine; drug dose titration; analgesics, opioid; drug substitution; hydromorphone; analgesia; morphine sulfate; naloxone; antihistaminic agent; fentanyl; oxycodone; diphenhydramine; hydroxyzine; opioid rotation; systemic opioids |
| Journal Title: | Journal of Opioid Management |
| Volume: | 3 |
| Issue: | 3 |
| ISSN: | 1551-7489 |
| Publisher: | Weston Medical Publishing, LLC |
| Date Published: | 2007-05-01 |
| Start Page: | 167 |
| End Page: | 170 |
| Language: | English |
| PUBMED: | 18027543 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 5" - "Export Date: 17 November 2011" - "Source: Scopus" |
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