Public access to protocols of contemporary cancer randomized clinical trials Research Letter
| Authors: | Babu, C.; Mell, L.; Lee, N.; Zakeri, K. |
| Title: | Public access to protocols of contemporary cancer randomized clinical trials |
| Abstract: | Access to randomized clinical trial (RCT) protocols is necessary for the interpretation and reproducibility of the study results, but protocol availability has been lacking. We determined the prevalence of protocol availability for all published cancer RCTs in January 2020. We found that only 36.1% (48/133) of RCTs had an accessible protocol and only 11.3% of RCTs (15/133) had a publicly accessible protocol that was not behind a paywall. Only 18.0% (24/133) of RCTs were published in conjunction with the protocol on the journal website. In conclusion, few cancer RCTs have an accessible research protocol. Journals should require publication of RCT protocols along with manuscripts to improve research transparency. © 2021, The Author(s). |
| Keywords: | cancer survival; event free survival; patient satisfaction; overall survival; letter; prevalence; information processing; publication; cancer therapy; patient care; access to information; patient decision making; disease control; clinical trials; supportive care; health literacy; randomized controlled trial (topic); access; symptom control; protocols; cancer; human; malignant neoplasm; journal impact factor; clinical trial protocol; cancer directed therapy; journal website; protocol availability |
| Journal Title: | Trials |
| Volume: | 22 |
| ISSN: | 1745-6215 |
| Publisher: | Biomed Central Ltd |
| Date Published: | 2021-06-27 |
| Start Page: | 418 |
| Language: | English |
| DOI: | 10.1186/s13063-021-05382-7 |
| PUBMED: | 34176506 |
| PROVIDER: | scopus |
| PMCID: | PMC8237482 |
| DOI/URL: | |
| Notes: | Letter -- Export Date: 2 August 2021 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work