Palpable lumps after mastectomy: Radiologic-pathologic review of benign and malignant masses Review


Authors: Al-Khalili, R.; Alzeer, A.; Nguyen, G. K.; Crane, E. P.; Song, J. H.; Jeon, J. L.; Nellamattathil, M.; Makariou, E. V.; Mango, V. L.
Review Title: Palpable lumps after mastectomy: Radiologic-pathologic review of benign and malignant masses
Abstract: Patients who have undergone mastectomy, with or without reconstruction, are not universally screened with mammography or US. Therefore, clinical breast examination by the physician and patientdetected palpable abnormalities are crucial for detecting breast cancer or recurrence. Diagnostic US is the first-line modality for evaluation of postmastectomy palpable masses, with occasional adjunct use of diagnostic mammography for confirming certain benign masses. In the setting of a negative initial imaging evaluation with continued clinical concern, diagnostic MRI may aid in improving sensitivity. Knowledge of the typical multimodality imaging appearances and locations of malignant palpable abnormalities—such as invasive carcinoma recurrence, cancer in residual breast tissue, radiation-induced sarcoma, and metastatic disease—is crucial in diagnosis and treatment of these entities. In addition, familiarity with the range of benign palpable postmastectomy processes—including fat necrosis, fat graft, seroma, granuloma, neuroma, fibrosis, and infection—may help avoid unnecessary biopsies and reassure patients. The authors review common and rare benign and malignant palpable masses in mastectomy patients, describe multimodality diagnostic imaging evaluation of each entity, review radiologic and pathologic correlation, and acquaint the radiologist with management when these findings are encountered. © RSNA, 2021.
Journal Title: RadioGraphics
Volume: 41
Issue: 4
ISSN: 0271-5333
Publisher: Radiological Society of North America, Inc.  
Date Published: 2021-07-01
Start Page: 967
End Page: 989
Language: English
DOI: 10.1148/rg.2021200161
PROVIDER: scopus
PMCID: PMC8262178
PUBMED: 33989071
DOI/URL:
Notes: Article -- Export Date: 2 August 2021 -- Source: Scopus
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  1. Victoria Lee Mango
    62 Mango