Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of urothelial cancer Guidelines


Authors: Galsky, M. D.; Balar, A. V.; Black, P. C.; Campbell, M. T.; Dykstra, G. S.; Grivas, P.; Gupta, S.; Hoimes, C. J.; Lopez, L. P.; Meeks, J. J.; Plimack, E. R.; Rosenberg, J. E.; Shore, N.; Steinberg, G. D.; Kamat, A. M.
Title: Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of urothelial cancer
Abstract: A number of immunotherapies have been developed and adopted for the treatment of urothelial cancer (encompassing cancers arising from the bladder, urethra, or renal pelvis). For these immunotherapies to positively impact patient outcomes, optimal selection of agents and treatment scheduling, especially in conjunction with existing treatment paradigms, is paramount. Immunotherapies also warrant specific and unique considerations regarding patient management, emphasizing both the prompt identification and treatment of potential toxicities. In order to address these issues, the Society for Immunotherapy of Cancer (SITC) convened a panel of experts in the field of immunotherapy for urothelial cancer. The expert panel developed this clinical practice guideline (CPG) to inform healthcare professionals on important aspects of immunotherapeutic treatment for urothelial cancer, including diagnostic testing, treatment planning, immune-related adverse events (irAEs), and patient quality of life (QOL) considerations. The evidence- and consensus-based recommendations in this CPG are intended to give guidance to cancer care providers treating patients with urothelial cancer. © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Keywords: urinary bladder neoplasms; urologic neoplasms; immunotherapy; guidelines as topic; antineoplastic protocols
Journal Title: Journal for ImmunoTherapy of Cancer
Volume: 9
Issue: 7
ISSN: 2051-1426
Publisher: Biomed Central Ltd  
Date Published: 2021-07-01
Start Page: e002552
Language: English
DOI: 10.1136/jitc-2021-002552
PROVIDER: scopus
PMCID: PMC8286774
PUBMED: 34266883
DOI/URL:
Notes: Article -- Export Date: 2 August 2021 -- Source: Scopus
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  1. Jonathan Eric Rosenberg
    510 Rosenberg