Authors: | Sheinfeld, J.; Sogani, P. |
Article Title: | Reoperative retroperitoneal surgery |
Abstract: | Although RPLND is both a diagnostic and therapeutic procedure, it must be performed with therapeutic intent. Adequacy of initial RPLND is a prognostic variable for clinical outcome. Effective cisplatin-based chemotherapy will not reliably compensate for suboptimal initial surgery. Many patients undergoing either primary RPLND or PC-RPLND will have unresected extratemplate disease if modified templates are used. Anatomic mapping studies, which provided the basis for modified templates, have significant limitations. Teratomatous elements are often found in the retroperitoneum of patients requiring reoperative surgery, which can be performed with acceptable morbidity in tertiary centers with experienced surgeons. The integration of chemotherapy and reoperative surgery can result in survival rates of almost 70% in patients with retroperitoneal relapse after initial suboptimal RPLND. © 2007 Elsevier Inc. All rights reserved. |
Keywords: | treatment outcome; survival analysis; cancer surgery; clinical trial; review; cisplatin; lymph node dissection; lymphatic metastasis; lymph node excision; lymphadenectomy; metastasis; multiple cycle treatment; neoplasm recurrence, local; morbidity; relapse; combination chemotherapy; vinblastine; statistical analysis; reoperation; testis tumor; testicular neoplasms; bleomycin; teratoma; testis cancer; germ cell tumor; clinical trials; retroperitoneal space; retroperitoneal surgery |
Journal Title: | Urologic Clinics of North America |
Volume: | 34 |
Issue: | 2 |
ISSN: | 0094-0143 |
Publisher: | W.B. Saunders Co-Elsevier Inc. |
Date Published: | 2007-05-01 |
Start Page: | 227 |
End Page: | 233 |
Language: | English |
DOI: | 10.1016/j.ucl.2007.02.008 |
PUBMED: | 17484927 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: UCNAD" - "Source: Scopus" |