Where lies the blame for resistance - Tumor or host? Journal Article
| Author: | Sawyers, C. L. |
| Article Title: | Where lies the blame for resistance - Tumor or host? |
| Abstract: | Cytokine signaling from the tumor microenvironment can allow leukemia cells to survive targeted imatinib therapy, in the first report of a non-autonomous resistance mechanism. © 2007 Nature Publishing Group. |
| Keywords: | nonhuman; animals; mice; imatinib; lung non small cell cancer; epidermal growth factor receptor; drug resistance, neoplasm; chronic myeloid leukemia; pyrimidines; protein p53; cancer therapy; protein kinase inhibitors; dna modification; leukemia cell; phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase; neoplasms, experimental; ligands; precursor cell lymphoblastic leukemia-lymphoma; short survey; chromosome translocation; microenvironment; hematopoietic stem cell; bcr abl protein; piperazines; acute lymphocytic leukemia; disease models, animal; fusion proteins, bcr-abl; scatter factor receptor; hypothesis; models, immunological; adp-ribosylation factor 1; receptors, cytokine |
| Journal Title: | Nature Medicine |
| Volume: | 13 |
| Issue: | 10 |
| ISSN: | 1078-8956 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2007-10-01 |
| Start Page: | 1144 |
| End Page: | 1145 |
| Language: | English |
| DOI: | 10.1038/nm1007-1144 |
| PUBMED: | 17917659 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 7" - "Export Date: 17 November 2011" - "CODEN: NAMEF" - "Source: Scopus" |
