Cancer: Mixing cocktails Journal Article


Author: Sawyers, C. L.
Article Title: Cancer: Mixing cocktails
Abstract: A major hurdle in treating cancer is that tumour cells acquire drug resistance. To overcome this problem, one strategy might be to fine-tune the right mixture of drugs that target specific molecules. ©2007 Nature Publishing Group.
Keywords: signal transduction; gene mutation; proto-oncogene proteins; erlotinib; cancer combination chemotherapy; drug targeting; imatinib; drug inhibition; gene amplification; lung non small cell cancer; antineoplastic combined chemotherapy protocols; lung neoplasms; epidermal growth factor receptor; lung cancer; receptor, epidermal growth factor; drug resistance; drug resistance, neoplasm; drug development; abelson kinase; dasatinib; cancer resistance; oncogene; glioblastoma; drug response; carcinogenicity; gefitinib; tumor cell; cancer relapse; short survey; tumor; epidermal growth factor receptor 3; phosphotransferase inhibitor; disease treatment; receptors, platelet-derived growth factor; receptors, growth factor; myeloid leukemia; drug mixture
Journal Title: Nature
Volume: 449
Issue: 7165
ISSN: 0028-0836
Publisher: Nature Publishing Group  
Date Published: 2007-10-25
Start Page: 993
End Page: 996
Language: English
DOI: 10.1038/449993a
PUBMED: 17960228
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 24" - "Export Date: 17 November 2011" - "CODEN: NATUA" - "Source: Scopus"
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  1. Charles L Sawyers
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