Adult-onset asthma and periocular xanthogranulomas in a patient with lymphoplasmacytic sclerosing pancreatitis Journal Article


Authors: Roggin, K. K.; Rudloff, U.; Klimstra, D. S.; Russell, L. A.; Blumgart, L. H.
Article Title: Adult-onset asthma and periocular xanthogranulomas in a patient with lymphoplasmacytic sclerosing pancreatitis
Abstract: The clinical syndrome of adult-onset asthma and periocular xanthogranulomas represents a rare systemic autoimmune disorder that has not been previously associated with autoimmune pancreatitis. Herein, we describe the case report of a 61-year-old man with the unique clinical association of adult-onset asthma, atopy, and periocular xanthogranulomas, who had previously been diagnosed with lymphoplasmacytic sclerosing pancreatitis. We have previously reported the case of a patient with lymphoplasmacytic sclerosing pancreatitis that developed postoperative inflammatory pseudotumor of the orbit. These unique, extrapancreatic, ocular manifestations of this disease add to the published observations that it is a systemic disorder with the potential for multiorgan involvement that may have a spectrum of clinical manifestations that includes adult-onset asthma and periocular xanthogranulomas. © 2007 Lippincott Williams & Wilkins, Inc.
Keywords: adult; human tissue; middle aged; human cell; clinical feature; anamnesis; case report; disease association; pancreatitis; asthma; eye disease; autoimmune diseases; onset age; age of onset; plasma cells; sclerosis; xanthogranuloma; multiple organ failure; histiocytes; granuloma, plasma cell; autoimmune pancreatitis; lymphoplasmacytic sclerosing pancreatitis; systemic disease; orbit; aapox; ocular lesions; eye xanthogranuloma; orbit pseudotumor; postoperative inflammation; orbital diseases; xanthomatosis
Journal Title: Pancreas
Volume: 34
Issue: 1
ISSN: 0885-3177
Publisher: Lippincott Williams & Wilkins  
Date Published: 2007-01-01
Start Page: 157
End Page: 160
Language: English
DOI: 10.1097/01.mpa.0000236737.84982.45
PUBMED: 17198199
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 6" - "Export Date: 17 November 2011" - "CODEN: PANCE" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Kevin King Roggin
    5 Roggin
  2. Leslie H Blumgart
    352 Blumgart
  3. David S Klimstra
    978 Klimstra