Caregiver–oncologist prognostic concordance, caregiver mastery, and caregiver psychological health and quality of life Journal Article

Authors: Loh, K. P.; Mohamed, M. R.; Kadambi, S.; Culakova, E.; Xu, H.; Magnuson, A.; Flannery, M.; Duberstein, P. R.; Epstein, R. M.; McHugh, C.; Nipp, R. D.; Trevino, K. M.; Sanapala, C.; Hall, B. A.; Canin, B.; Gayle, A. A.; Conlin, A.; Bearden, J. 3rd; Mohile, S. G.
Article Title: Caregiver–oncologist prognostic concordance, caregiver mastery, and caregiver psychological health and quality of life
Abstract: Background: Caregivers of adults with cancer often report a different understanding of the patient's prognosis than the oncologist. We examine the associations of caregiver–oncologist prognostic concordance with caregiver depressive symptoms, distress, and quality of life (QoL). We also explore whether these relationships differed by caregiver environment mastery, an individual's sense of control, and effectiveness in managing life situations. Materials and Methods: We used data from a national geriatric assessment cluster-randomized trial (URCC 13070) that recruited patients aged 70 years and older with incurable cancer considering any line of cancer treatment at community oncology practices, their caregivers, and their oncologists. At enrollment, caregivers and oncologists estimated the patient's prognosis (0–6 months, 7–12 months, 1–2 years, 2–5 years, and >5 years; identical responses were concordant). Caregivers completed the Ryff's environmental mastery at enrollment. At 4–6 weeks, caregivers completed the Patient Health Questionnaire-2 (depressive symptoms), distress thermometer, and 12-Item Short-Form Health Survey (quality of life [QoL]). We used generalized estimating equations in models adjusted for covariates. We then assessed the moderation effect of caregiver mastery. Results: Of 411 caregiver–oncologist dyads (mean age = 66.5 years), 369 provided responses and 28% were concordant. Prognostic concordance was associated with greater caregiver depressive symptoms (β = 0.30; p =.04) but not distress or QoL. A significant moderation effect for caregiver depressive symptoms was found between concordance and mastery (p =.01). Specifically, among caregivers with low mastery (below median), concordance was associated with greater depressive symptoms (β = 0.68; p =.003). Conclusions: Caregiver–oncologist prognostic concordance was associated with caregiver depressive symptoms. We found a novel moderating effect of caregiver mastery on the relationship between concordance and caregiver depressive symptoms. Implications for Practice: Caregiver–oncologist prognostic concordance is associated with greater caregiver depressive symptoms, particularly in those with low caregiver mastery. When discussing prognosis with caregivers, physicians should be aware that prognostic understanding may affect caregiver psychological health and should assess their depressive symptoms. In addition, while promoting accurate prognostic understanding, physicians should also identify strengths and build resilience among caregivers. © 2021 AlphaMed Press
Keywords: aged; quality of life; health survey; cancer therapy; questionnaire; depression; caregiver; life expectancy; mental health; geriatric assessment; caregivers; randomized controlled trial (topic); older patients; oncologist; depressive symptoms; caregiver support; very elderly; prognosis; human; male; female; article; psychological well-being; short form 12; environmental mastery; prognostic concordance; patient health questionnaire 2
Journal Title: The Oncologist
Volume: 26
Issue: 4
ISSN: 1083-7159
Publisher: AlphaMed Press  
Date Published: 2021-04-01
Start Page: 310
End Page: 317
Language: English
DOI: 10.1002/onco.13699
PUBMED: 33523583
PROVIDER: scopus
PMCID: PMC8018313
Notes: Article -- Export Date: 3 May 2021 -- Source: Scopus
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MSK Authors
  1. Kelly M Trevino
    22 Trevino