Radiation dose-volume effects for liver SBRT Review


Authors: Miften, M.; Vinogradskiy, Y.; Moiseenko, V.; Grimm, J.; Yorke, E.; Jackson, A.; Tomé, W. A.; Ten Haken, R. K.; Ohri, N.; Méndez Romero, A.; Goodman, K. A.; Marks, L. B.; Kavanagh, B.; Dawson, L. A.
Review Title: Radiation dose-volume effects for liver SBRT
Abstract: Stereotactic body radiation therapy (SBRT) has emerged as an effective, noninvasive treatment option for primary liver cancer and metastatic disease occurring in the liver. Although SBRT can be highly effective for establishing local control in hepatic malignancies, a tradeoff exists between tumor control and normal tissue complications. The objective of the present study was to review the normal tissue dose-volume effects for SBRT-induced liver and gastrointestinal toxicities and derive normal tissue complication probability models. © 2018 Elsevier Inc.
Keywords: radiotherapy; radiation effects; local control; disease control; stereotactic body radiation therapy; diseases; tissue; metastatic disease; normal-tissue complication probability models; tumor control; gastrointestinal toxicities; noninvasive medical procedures; primary liver cancers; non-invasive treatment
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 110
Issue: 1
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 2021-05-01
Start Page: 196
End Page: 205
Language: English
DOI: 10.1016/j.ijrobp.2017.12.290
PUBMED: 29482870
PROVIDER: scopus
PMCID: PMC6095822
DOI/URL:
Notes: Article -- Export Date: 3 May 2021 -- Source: Scopus
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  1. Andrew Jackson
    253 Jackson
  2. Ellen D Yorke
    450 Yorke
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