Authors: | Offit, K.; Thom, P. |
Article Title: | Ethical and legal aspects of cancer genetic testing |
Abstract: | As a result of the increasing effectiveness of cancer screening and preventive interventions, ethical issues, as well as legal liabilities, are increasingly associated with cancer genetic testing. These issues include the possible "duty to warn" relatives of inherited cancer risk, the appropriateness of testing of children and embryos, equity of access to genetics services, and potential harms of testing including the risk of genetic discrimination. An approach to these and other ethical challenges will be presented, drawing not only on recent case law but also on a broader bioethical framework. © 2007 Elsevier Inc. All rights reserved. |
Keywords: | cancer risk; genetic analysis; neoplasms; genetic predisposition to disease; cancer prevention; genetic variability; cancer screening; risk assessment; law; legal aspect; cancer genetics; laboratory test; informed consent; genetic screening; ethics; genetic counseling; government regulation; disclosure; molecular diagnostic techniques; privacy; paternalism; ethics, medical; beneficence; genetic discrimination; genetic service; genetic services |
Journal Title: | Seminars in Oncology |
Volume: | 34 |
Issue: | 5 |
ISSN: | 0093-7754 |
Publisher: | Elsevier Inc. |
Date Published: | 2007-10-01 |
Start Page: | 435 |
End Page: | 443 |
Language: | English |
DOI: | 10.1053/j.seminoncol.2007.07.007 |
PUBMED: | 17920900 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 12" - "Export Date: 17 November 2011" - "CODEN: SOLGA" - "Source: Scopus" |