Brain metastases: Old problem, new strategies Journal Article

  


Authors: Nguyen, T. D.; Abrey, L. E.
Article Title: Brain metastases: Old problem, new strategies
Abstract: Brain metastases from breast cancer are a common complication of the disease and alter the management of patients more than any other site of distant progression. Certain subgroups of patients are at high risk for developing CNS disease, warranting targeted research and perhaps screening for occult disease. Data from studies that include other solid tumor histologies provide the bulk of supporting evidence for the use of therapies, such as steroids, antiepileptic drugs, surgery, and radiation. However, there are several issues specific to brain metastases from breast cancer illustrating that this disease should be considered pathophysiologically distinct, and future research should be tailored accordingly. © 2007.
Keywords: prednisone; clinical feature; clinical trial; review; doxorubicin; fluorouracil; hypertension; side effect; antineoplastic agents; paclitaxel; methotrexate; nuclear magnetic resonance imaging; brain neoplasms; magnetic resonance imaging; gene targeting; computer assisted tomography; allergy; cancer screening; cyclophosphamide; steroid; vincristine; breast neoplasms; risk factor; central nervous system; docetaxel; hyperglycemia; hypokalemia; hepatomegaly; breast carcinoma; pancreatitis; radiosurgery; acne; brain metastasis; tamoxifen; epirubicin; cataract; craniotomy; seizure; osteoporosis; immunosuppressive treatment; psychosis; wound healing impairment; congestive heart failure; bone necrosis; impotence; clinical trials; mood disorder; myopathy; adrenal insufficiency; exophthalmos; lipomatosis; moon face; typhlitis; intracranial hypertension; amenorrhea; peptic ulcer; folliculitis; metabolic alkalosis; pathologic fracture; sodium retention
Journal Title: Hematology/Oncology Clinics of North America
Volume: 21
Issue: 2
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 2007-04-01
Start Page: 369
End Page: 388
Language: English
DOI: 10.1016/j.hoc.2007.03.009
PUBMED: 17512454
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-34248530545&partnerID=40&md5=2076469ad80824522a46039d25d9e773
Notes: --- - "Export Date: 17 November 2011" - "CODEN: HCNAE" - "Source: Scopus"
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MSK Authors
  1. Teri Dzung Nguyen
    7 Nguyen
  2. Lauren E Abrey
    278 Abrey
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