Authors: | Iacobuzio-Donahue, C. A.; Litchfield, K.; Swanton, C. |
Title: | Intratumor heterogeneity reflects clinical disease course |
Abstract: | Intratumoral genetic heterogeneity of driver somatic mutations is present in a variety of tumor types, yet the extent of heterogeneity is variable. We propose that this variation is a reflection of the inherent biology of a given tumor type, representing the pace of metastatic dissemination and hence clinical disease course. |
Keywords: | evolutionary |
Journal Title: | Nature Cancer |
Volume: | 1 |
Issue: | 1 |
ISSN: | 2662-1347 |
Publisher: | Nature Research |
Date Published: | 2020-01-01 |
Start Page: | 3 |
End Page: | 6 |
Language: | English |
ACCESSION: | WOS:000610411800002 |
DOI: | 10.1038/s43018-019-0002-1 |
PROVIDER: | wos |
PUBMED: | 35121835 |
Notes: | Editorial Material -- Source: Wos |