Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons Review


Authors: Goldstein, S. D.; Heaton, T. E.; Bondoc, A.; Dasgupta, R.; Abdelhafeez, A.; Davidoff, A. M.; Lautz, T. B.
Review Title: Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons
Abstract: Fluorescence-guided surgery (FGS) is an increasingly available and popular method of visual field augmentation. The basic premise of FGS entails injection of fluorescent indocyanine green (ICG) and subsequent detection with a near-infrared (NIR) camera. For pediatric surgical oncologists, FGS remains experimental but is a promising modality for identifying tumor margins, locating metastases, performing sentinel lymph node biopsies, protecting peritumoral structures of interest, and facilitating reconstruction. Familiarity with basic ICG pharmacokinetics and NIR detection optics is critical for surgeons wishing to judiciously use FGS, as its success is firmly grounded in a thorough understanding of its capabilities and limitations. In this practical guide, we outline several well-described and innovative FGS applications by disease type, including their methods of administration, modes of detection, and typical ICG dosing paradigms. Level of Evidence: V © 2020 Elsevier Inc.
Keywords: sentinel lymph node; fluorescence; metastasectomy; indocyanine green
Journal Title: Journal of Pediatric Surgery
Volume: 56
Issue: 2
ISSN: 0022-3468
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2021-02-01
Start Page: 215
End Page: 223
Language: English
DOI: 10.1016/j.jpedsurg.2020.10.013
PUBMED: 33189300
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 March 2021 -- Source: Scopus
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  1. Todd Erin Heaton
    44 Heaton