| Abstract: |
Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it—like other mammalian inflammasomes characterized thus far—evolved to detect and respond to a single danger-associated molecular pattern. © 2021 Elsevier Inc. Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it—like other mammalian inflammasomes characterized thus far—evolved to detect and respond to a single danger-associated molecular pattern. © 2021 Elsevier Inc. |
