Abstract: |
The therapeutic options are limited for patients presenting with locally symptomatic airway compromise following definitive surgery and/or irradiation. Most of these patients will also have hemoptysis, often severe enough to cause near-asphyxia. Repeat external beam irradiation is of some value, but palliation is modest and of very short duration. The application of laser debulking is being utilized increasingly, but the improvement is not usually longer than 3 months in duration, and repetition of this treatment becomes less effective because the obstruction occurs over a greater distance. Other treatment methods utilized in the past aimed at obtaining more sustained palliation are transbronchial excision or cauterization and laser photoradiation. Intraluminal brachytherapy with implantation of radioactive pellets into the tumor or with a remotely controlled high-intensity radioactive source has also been used increasingly in an attempt to control the tumor as well as relieve symptoms. This article will review these new innovative methods of intraluminal brachytherapy in lung cancer. |