Intraluminal irradiation in bronchogenic carcinoma Journal Article


Authors: Nori, D.; Hilaris, B. S.; Martini, N.
Article Title: Intraluminal irradiation in bronchogenic carcinoma
Abstract: The therapeutic options are limited for patients presenting with locally symptomatic airway compromise following definitive surgery and/or irradiation. Most of these patients will also have hemoptysis, often severe enough to cause near-asphyxia. Repeat external beam irradiation is of some value, but palliation is modest and of very short duration. The application of laser debulking is being utilized increasingly, but the improvement is not usually longer than 3 months in duration, and repetition of this treatment becomes less effective because the obstruction occurs over a greater distance. Other treatment methods utilized in the past aimed at obtaining more sustained palliation are transbronchial excision or cauterization and laser photoradiation. Intraluminal brachytherapy with implantation of radioactive pellets into the tumor or with a remotely controlled high-intensity radioactive source has also been used increasingly in an attempt to control the tumor as well as relieve symptoms. This article will review these new innovative methods of intraluminal brachytherapy in lung cancer.
Keywords: adult; aged; major clinical study; review; methodology; radiotherapy; lung tumor; brachytherapy; technique; therapy; airway obstruction; respiratory system; human
Journal Title: Surgical Clinics of North America
Volume: 67
Issue: 5
ISSN: 0039-6109
Publisher: Elsevier Inc.  
Date Published: 1987-10-01
Start Page: 1093
End Page: 1102
Language: English
DOI: 10.1016/s0039-6109(16)44347-1
PUBMED: 2442822
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus
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  1. Nael   Martini
    105 Martini
  2. Basil B Hilaris
    43 Hilaris
  3. Dattatreyudu Nori
    38 Nori