Mammographic findings after breast cancer treatment with local excision and definitive irradiation Journal Article
| Authors: | Dershaw, D. D.; Shank, B.; Reisinger, S. |
| Article Title: | Mammographic findings after breast cancer treatment with local excision and definitive irradiation |
| Abstract: | Following local excision and definitive irradiation of 163 breast cancers in 160 women, alterations in mammographic patterns were observed for up to 7 years. Skin thickening was observed in 96% of mammograms obtained within 1 year of completing therapy and was most pronounced in women treated with iridium implant, chemotherapy, or axillary dissection. In 76% of mammograms, alterations in the parenchymal pattern, including coarsening of stroma and increased breast density, were seen at 1 year. Neither skin nor parenchymal changes progressed after 1 year. Within 3 years of treatment the parenchymal density, which usually regressed, did not change in all patients. At 3 years skin thickness and the parenchymal pattern had returned to normal in less than 50% of the breasts of these women. Scars developed in approximately one-quarter of women. They were present on the initial post-treatment mammogram and remained unchanged on serial studies. Coarse, benign calcifications also developed in the breasts of about one-quarter of women. Microcalcifications developed in 11 breasts; biopsy specimens of six were benigh. Benign microcalcifications may be related to therapy. |
| Keywords: | cancer surgery; major clinical study; treatment; follow up; breast cancer; breast; biopsy; histology; mammography; diagnosis; irradiation; therapy; calcification; human; priority journal |
| Journal Title: | Radiology |
| Volume: | 164 |
| Issue: | 2 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 1987-08-01 |
| Start Page: | 455 |
| End Page: | 461 |
| Language: | English |
| DOI: | 10.1148/radiology.164.2.3037592 |
| PUBMED: | 3037592 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
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