Operative management of primary epithelial ovarian cancer Journal Article


Authors: Leitao, M. M. Jr; Chi, D. S.
Article Title: Operative management of primary epithelial ovarian cancer
Abstract: Surgery plays an integral part in the primary management of early-stage and advanced-stage epithelial ovarian cancer. Surgical staging is essential for disease grossly confined to the ovaries or pelvis. Comprehensive surgical staging often results in upstaging of patients who were presumed to be at an early stage. Accurate staging has an impact on prognosis and treatment strategies. Optimal surgical cytoreduction leads to improved outcomes in patients with advanced disease; before initiation of chemotherapy, it offers the most favorable outcome and should be offered to all patients. Intraperitoneal catheters for postoperative chemotherapy instillation may be offered and placed at the time of cytoreduction. Neoadjuvant chemotherapy and interval cytoreduction are a possibility for patients who are not amenable to an optimal cytoreduction based on preoperative findings or in those who are at extremely high risk for surgery. Copyright © 2007 by Current Medicine Group LLC.
Keywords: cancer survival; treatment outcome; overall survival; clinical trial; review; patient selection; treatment planning; clinical trials as topic; adjuvant therapy; cancer adjuvant therapy; disease free survival; cancer staging; lymph node metastasis; antineoplastic agent; lymph node dissection; paraaortic lymph node; pelvis lymph node; neoplasm staging; preoperative evaluation; salpingooophorectomy; lymphadenectomy; cytoreductive surgery; ovarian neoplasms; accuracy; tumor localization; quality of life; multiple cycle treatment; ovary cancer; melphalan; high risk patient; epithelial cells; platinum complex; taxane derivative; abdominal hysterectomy; peritoneal catheter
Journal Title: Current Oncology Reports
Volume: 9
Issue: 6
ISSN: 1523-3790
Publisher: Springer  
Date Published: 2007-11-01
Start Page: 478
End Page: 484
Language: English
DOI: 10.1007/s11912-007-0067-3
PUBMED: 17991356
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 6" - "Export Date: 17 November 2011" - "CODEN: CORUA" - "Source: Scopus"
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MSK Authors
  1. Dennis S Chi
    658 Chi
  2. Mario Leitao
    511 Leitao