Monitoring endoscopic treatment of superficial bladder carcinoma by postoperative urinary cytology Journal Article


Authors: Badalament, R. A.; Gay, H.; Cibas, E. S.; Herr, H. W.; Whitmore, W. F. Jr; Fair, W. R.; Melamed, M. R.
Article Title: Monitoring endoscopic treatment of superficial bladder carcinoma by postoperative urinary cytology
Abstract: Transurethral resection was the only modality of treatment in 39 patients with long-standing, recurrent, superficial bladder carcinoma. Postoperative urinary cytology was performed within 3 days of each endoscopy. Tumor recurrence was defined by the presence of a positive biopsy or visible papillary tumors on followup cystoscopic examination. Tumor recurred in 38 patients (97.4 per cent) and 1 patient (2.6 per cent) has remained free of disease 74 months following transient positive postoperative cytology. Among the 38 recurrences 15 (39.5 per cent) were positive, 3 (7.9 per cent) suspicious and 20 (52.6 per cent) negative at the postoperative cytological examination. The interval to recurrence did not differ significantly among the 3 groups. The failure of a negative postoperative cytology study to predict a durable response to treatment by transurethral resection reflects the polychronotopic nature of superficial bladder tumors in this select patient population and suggests the need for adjuvant therapy.
Keywords: clinical article; recurrent cancer; cytology; biopsy; histology; diagnosis; transurethral resection; bladder carcinoma; therapy; bladder; male genital system; superficial cancer; human
Journal Title: Journal of Urology
Volume: 138
Issue: 4
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 1987-10-01
Start Page: 760
End Page: 762
Language: English
DOI: 10.1016/s0022-5347(17)43364-7
PUBMED: 3656527
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus
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  1. Harry W Herr
    594 Herr
  2. William R Fair
    342 Fair
  3. Willet F. Whitmore Jr
    139 Whitmore
  4. Myron Melamed
    148 Melamed