Phase II trial of etoposide in APUD tumors Journal Article
| Authors: | Kelsen, D.; Fiore, J.; Heelan, R.; Cheng, E.; Magill, G. |
| Article Title: | Phase II trial of etoposide in APUD tumors |
| Abstract: | Thirty-three patients with advanced, metastatic APUD tumors (islet cell, carcinoid, or medullary carcinomas of the thyroid) were treated with etoposide as a single agent. Of 29 evaluable patients, four (14%) had partial responses (95% confidence limits, 1%-26%). Toxic effects seen were those previously reported for etoposide as a single agent. Etoposide has activity in APUD tumors; further studies with this agent are indicated. |
| Keywords: | adult; cancer chemotherapy; clinical article; aged; middle aged; advanced cancer; drug efficacy; skin toxicity; metastasis; etoposide; nausea; vomiting; carcinoembryonic antigen; calcitonin; gastrointestinal toxicity; carcinoid; thyroid neoplasms; drug therapy; small intestine; alopecia; carcinoid tumor; adverse drug reaction; therapy; intravenous drug administration; pancreas islet cell carcinoma; pancreas islet cell tumor; endocrine system; thyroid medullary carcinoma; bone marrow depression; gastrins; drug evaluation; intoxication; adenoma, islet cell; humans; human; male; female; priority journal; hydroxyindoleacetic acid; apudoma; blood and hemopoietic system |
| Journal Title: | Cancer Treatment Reports |
| Volume: | 71 |
| Issue: | 3 |
| ISSN: | 0361-5960 |
| Publisher: | National Cancer Institute |
| Date Published: | 1987-03-01 |
| Start Page: | 305 |
| End Page: | 307 |
| Language: | English |
| PUBMED: | 2434226 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 5 February 2021 -- Source: Scopus |
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