Generalized lymphadenopathy with morphologic features of Castleman's disease in an HIV‐positive man Journal Article

  


Authors: Lowenthal, D. A.; Filippa, D. A.; Richardson, M. E.; Bertoni, M.; Straus, D. J.
Article Title: Generalized lymphadenopathy with morphologic features of Castleman's disease in an HIV‐positive man
Abstract: In recent years the literature has described a highly lethal “multicentric” variant of classic Castleman's disease (CD) with similar hyperplastic angio‐follicular morphologic features. A 44‐year‐old man who was not known to be part of any established high‐risk group for the acquired immune deficiency syndrome (AIDS) presented with clinical and laboratory features similar to “multicentric” CD. Serologic testing revealed antibody to the human immunodeficiency virus (HIV) by Western blot analysis. It is suggested that “multicentric” CD may be part of the clinicopathologic spectrum of HIV infection, and there should be a high index of suspicion for HIV in patients presenting with generalized lymphadenopathy and histopathologic features of CD. Copyright © 1987 American Cancer Society
Keywords: adult; human cell; histopathology; case report; lymph nodes; diagnosis, differential; lung neoplasms; histology; lymphatic system; diagnosis; human immunodeficiency virus; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; sarcoma, kaposi; lymphadenopathy; hiv; opportunistic infections; antibodies, viral; hiv antibodies; angiofollicular lymph node hyperplasia; giant lymph node hyperplasia; human; male
Journal Title: Cancer
Volume: 60
Issue: 10
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1987-11-15
Start Page: 2454
End Page: 2458
Language: English
DOI: 10.1002/1097-0142(19871115)60:10<2454::Aid-cncr2820601018>3.0.Co;2-i
PUBMED: 3478119
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023635761&doi=10.1002%2f1097-0142%2819871115%2960%3a10%3c2454%3a%3aAID-CNCR2820601018%3e3.0.CO%3b2-I&partnerID=40&md5=a66b14ba272b5f0d4fca93314a8b0880
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus
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MSK Authors
  1. Daniel A Filippa
    148 Filippa
  2. David J Straus
    356 Straus
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