Distinguishing features of primary hyperparathyroidism in patients with breast cancer Journal Article


Authors: Axelrod, D. M.; Bockman, R. S.; Wong, G. Y.; Osborne, M. P.; Kinne, D. W.; Brennan, M. F.
Article Title: Distinguishing features of primary hyperparathyroidism in patients with breast cancer
Abstract: Thirty‐five women with breast cancer and primary hyperparathyroidism (1°HFT) were admitted to Memorial Hospital during a 25‐year period. The incidence of primary hyperparathyroidism in the breast cancer patients was similar to the incidence in the total patient population at Memorial Sloan‐Kettering Cancer Center (0.15% and 0.14%, respectively). The patients with 1°HPT disease had clinical findings which distinguished them from those patients with cancer‐related hypercalcemia. Eighty percent of the breast cancer patients with primary hyperparathyroidism had earlier stage disease (Stage 0, Stage 1, Stage 2); whereas 97% of the patients with breast cancer and hypercalcemia (not due to 1°HPT) had advanced disease. There appeared to be a trend towards improved survival in the breast cancer patients with primary hyperparathyroidism when compared to patients of similar stage of disease who did not have parathyroid disease. Copyright © 1987 American Cancer Society
Keywords: survival; adult; clinical article; retrospective studies; cancer staging; lymph node metastasis; lymphatic metastasis; neoplasm staging; breast cancer; breast; hypercalcemia; breast neoplasms; retrospective study; time; time factors; breast tumor; diagnosis; hyperparathyroidism; endocrine system; primary hyperparathyroidism; human; female; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title: Cancer
Volume: 60
Issue: 7
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1987-10-01
Start Page: 1620
End Page: 1624
Language: English
DOI: 10.1002/1097-0142(19871001)60:7<1620::Aid-cncr2820600733>3.0.Co;2-3
PUBMED: 3621132
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus -- Acknowldegement: Douglas Chapman, MS, Division of Biostatistics, for assisting in statistical analysis, and Marisol Perez for preparing this manuscript
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MSK Authors
  1. Murray F Brennan
    1059 Brennan
  2. George Y. Wong
    89 Wong
  3. David Kinne
    64 Kinne
  4. Michael P. Osborne
    61 Osborne
  5. Richard Bockman
    24 Bockman