Influence of the extent of resection on survival after curative treatment of gastric carcinoma: A retrospective multivariate analysis Journal Article

  

Authors:	Shiu, M. H.; Moore, E.; Sanders, M.; Huvos, A.; Freedman, B.; Goodbold, J.; Chaiyaphruk, S.; Wesdorp, R.; Brennan, M. F.
Article Title:	Influence of the extent of resection on survival after curative treatment of gastric carcinoma: A retrospective multivariate analysis
Abstract:	The therapeutic value of extensive gastric resection and regional lymphadenectomy in the curative treatment of gastric adenocarcinoma is controversial. We undertook a retrospective study of 210 patients treated with curative intent from 1960 to 1980. A multivariate survival analysis using the Cox model revealed five significant variables predictive of death from gastric cancer—two inherent pathologic factors: (1) nonpyloric site and (2) metastases in more than three lymph nodes, and three treatment factors that could often be controlled by the surgeon: (3) microscopic positive gastric resection margin, (4) inadequate lymphadenectomy, and (5) total gastrectomy. These observations reaffirm the value of wide gastric resection and adequate lymphadenectomy but argue against a general policy of elective total gastrectomy in the curative treatment of gastric carcinoma. © 1987, American Medical Association. All rights reserved.
Keywords:	retrospective studies; major clinical study; lymph node excision; lymphadenectomy; adenocarcinoma; statistics; retrospective study; gastrectomy; stomach cancer; stomach neoplasms; prognosis; human
Journal Title:	Archives of Surgery
Volume:	122
Issue:	11
ISSN:	0004-0010
Publisher:	American Medical Association
Date Published:	1987-11-01
Start Page:	1347
End Page:	1351
Language:	English
DOI:	10.1001/archsurg.1987.01400230135024
PUBMED:	3675199
PROVIDER:	scopus
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0023612405&doi=10.1001%2farchsurg.1987.01400230135024&partnerID=40&md5=edca3e3f4e7231b58248c034436a950e
Notes:	Article -- Export Date: 5 February 2021 -- Source: Scopus

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