Biological performance in β‐thal heterozygotes and normals: Results of a longitudinal comparison in a former malarial environment Journal Article


Authors: Canella, R.; Barbujani, G.; Cucchi, P.; Siniscalco, M.; Vullo, C.; Barrai, I.
Article Title: Biological performance in β‐thal heterozygotes and normals: Results of a longitudinal comparison in a former malarial environment
Abstract: Families of β‐thal heterozygotes and of normals studied in 1956 by Silvestroni and Bianco in the small town of Berra near Ferrara were studied again in 1981–85. It was possible to compare mortality, fertility, and migration, in the two groups of heterozygotes and normals after the lapse of one generation. At the power of resolution of the sample available and of the methods used, no difference was visible. However, it was possible to establish the upper limits of the differences in average age at death and in average fertility at the 5% level of significance. Copyright © 1987, Wiley Blackwell. All rights reserved
Keywords: genetics; mortality; age factors; heterozygote; age; longitudinal studies; thalassemia; fertility; migration; longitudinal study; malaria; italy; emigration and immigration; humans; human; article
Journal Title: Annals of Human Genetics
Volume: 51
Issue: 4
ISSN: 0003-4800
Publisher: Wiley-Blackwell Publishing, Inc.  
Date Published: 1987-10-01
Start Page: 337
End Page: 343
Language: English
DOI: 10.1111/j.1469-1809.1987.tb01068.x
PUBMED: 3447516
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 5 February 2021 -- Source: Scopus
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