Immune escape in prostate cancer: Known and predicted mechanisms and targets Review
| Authors: | Reva, B. A.; Omelchenko, T.; Nair, S. S.; Tewari, A. K. |
| Review Title: | Immune escape in prostate cancer: Known and predicted mechanisms and targets |
| Abstract: | Complex immune evasion mechanisms and lack of biomarkers predicting responsiveness to immune checkpoint blockade therapies compromise immunotherapy's therapeutic efficacy for patients with prostate cancer. The authors review established and nominated immune evasion mechanisms in prostate cancer and discuss how the precise treatment strategies can be developed to improve efficacy of immunotherapy. © 2020 Elsevier Inc. |
| Keywords: | prostate cancer; immunotherapy; immune evasion; ifn-γ signaling |
| Journal Title: | Urologic Clinics of North America |
| Volume: | 47 |
| Issue: | 4 Suppl. |
| ISSN: | 0094-0143 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2020-11-01 |
| Start Page: | e9 |
| End Page: | e16 |
| Language: | English |
| DOI: | 10.1016/j.ucl.2020.10.004 |
| PROVIDER: | scopus |
| PUBMED: | 33446324 |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 February 2021 -- Source: Scopus |
