Unexpected long-term survival without evidence of disease after salvage chemotherapy for recurrent metastatic cervical cancer: A case series Journal Article
| Authors: | Khoury-Collado, F.; Bowes, R. J. ; Jhamb, N.; Aghajanian, C.; Abu-Rustum, N. R. |
| Article Title: | Unexpected long-term survival without evidence of disease after salvage chemotherapy for recurrent metastatic cervical cancer: A case series |
| Abstract: | Background.: The prognosis of recurrent metastatic cervical cancer is extremely poor. Platinum-based palliative chemotherapy constitutes the mainstay of treatment. Cure is extremely rare. Case.: We present 3 cases of recurrent metastatic cervical cancer in which the patients remain disease-free many years after completing salvage chemotherapy and surgery. The patients remain with no evidence of disease at 6, 7, and 13 years, respectively, following recurrence. Conclusion.: In rare cases, an unexpected complete clinical remission and long-term survival without evidence of disease may be achieved in patients with recurrent metastatic cervical cancer treated with multimodal therapy. © 2007 Elsevier Inc. All rights reserved. |
| Keywords: | adult; cancer chemotherapy; human tissue; disease-free survival; middle aged; cancer surgery; histopathology; case report; salvage therapy; carcinoma, squamous cell; cisplatin; fluorouracil; paclitaxel; recurrent cancer; carboplatin; metastasis; multiple cycle treatment; neoplasm recurrence, local; antineoplastic combined chemotherapy protocols; ifosfamide; survival time; uterine cervix cancer; uterine cervical neoplasms; cervical carcinoma; recurrent cervical cancer; salvage chemotherapy |
| Journal Title: | Gynecologic Oncology |
| Volume: | 105 |
| Issue: | 3 |
| ISSN: | 0090-8258 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2007-06-01 |
| Start Page: | 823 |
| End Page: | 825 |
| Language: | English |
| DOI: | 10.1016/j.ygyno.2007.02.009 |
| PUBMED: | 17363045 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: GYNOA" - "Source: Scopus" |
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